Welcome to the Schwalbe Lab

Our group is interested in the determination of structure and dynamics of a variety of molecules of chemical and biological interest, organic synthesis of biologically relevant compounds and nmr method development.

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Latest publications

Commun Chem

, 2026

AI-assisted fragment-based drug discovery of SARS-CoV-2 macrodomain binders validated by NMR and X-ray crystallography

E. Aledavood, S. Ramos-Inza, J. Born, H. Berg, J.M. Köhler, A. Niesteruk, S. Sreeramulu, A.K. Thompson, H. Mikolajek, J. Sandy, J. Sanchez-Weatherby, S. Wang, E.P. Williams, M.A. Walsh, M.A. Hough, H. Schwalbe, A. Martínez, C. Gil

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Chemistry

, 2026

Rapid access to photoswitchable RNA binders: fluorination enhances protein rescue by exon inclusion

L. Zhang, N. Djokovic, A. Herr, A. Wacker, E.S. Hay, D. Santana, A.E. Hargrove, H. Schwalbe, K. Nikolic, F. Abendroth, O Vázquez

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