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Journal/Book: Angew. Chem. Int. Ed. Engl.
Published: 2010
Pages: 5410 - 5412
Volume: 49
Accession no.: 195

Highlight: The molecular mechanism of spider silk formation

Robert Silvers, Buhr, F, Harald Schwalbe
How spiders enmesh their prey: The NMR spectroscopic determination of the C-terminal non-repeat domain of Araneus diadematus fibroin 3 (ADF-3), a spider silk protein, was recently reported. At the same time, the X-ray structure determination of the N-terminal non-repeat domain was reported. Both structures provide key insights into fiber formation upon shear stress and pH changes, including the templating effect on fiber morphology.
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Prof. Dr. Harald Schwalbe
Institut für Organische Chemie und Chemische Biologie
Johann Wolfgang Goethe Universität
Max-von-Laue-Str. 7
D-60438 Frankfurt am Main
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