Publications

Nucl. Acids Res.
, 2024
The 5’-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH
S. Toews, A. Wacker, E. Faison, E. Duchardt-Ferner, C. Richter, C. Mathieu, S. Battaro, Q. Zhang, H. Schwalbe
RNA
, 2024
NMR characterization and ligand binding site of the stem loop 2 motif (s2m) from the Delta variant of SARS-CoV-2.
T. Matzel, M. Wirtz Martin, A. Herr, A. Wacker, C. Richter, S. Sreeramulu, H. Schwalbe
Nucl. Acids Res.
, 2024
Structure of an internal loop motif with three consecutive U•U mismatches from stem-loop 1 in the 3′-UTR of the SARS-CoV-2 genomic RNA
J. Vögele, E. Duchardt-Ferner, J.K. Bains, B. Knezic, A. Wacker, C. Sich, J. Weigand, J. Sponer, H. Schwalbe, M. Krepl, J. Wöhnert
ChemBioChem
, 2024
Biophysical Investigation of RNA•DNA:DNA triple helix and RNA:DNA heteroduplex formation by the lncRNAs MEG3 and Fendrr
Krause NM, Bains JK, Blechar J, Richter C, Bessi I, Grote P, Leisegang MS, Brandes RP, Schwalbe H
Chem. Commun
, 2024
Guanosine-based hydrogel as a supramolecular scaffold for template-assisted macrocyclization
B, Lala, R. Chaudhuri, T. Prasanth, I. Burkhart, H. Schwalbe, J. Dash
ACS Chem Biol
, 2024
Shine-Dalgarno Accessibility Governs Ribosome Binding to the Adenine Riboswitch
Blechar J, de Jesus V, Fürtig B, Hengesbach M, Schwalbe H.
RSC Med. Chem.
, 2024
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection
X. Jalencas, H. Berg, L.O. Espeland, S. Sreeramulu, F. Kinnen, C. Richter, C. Georgiou, V. Yadrykhinsky, E. Specker, K. Jaudzems, T. Miletic, R. Harmel, P. Gribbon, H. Schwalbe*, R. Brenk*, A. Jirgensons*, A. Zaliani*, J. Mestres*
ACS Chem Biol
, 2024
Targeting main protease (Mpro, nsp5) by growth of fragment scaffolds exploiting structure-based methodologies.
N. Altincekic, N. Jores, F. Löhr, C. Richter, C. Ehrhardt, M.J.J. Blommers, H. Berg, S. Öztürk, S.L. Gande, V. Linhard, J. Orts, M.J. Abi Saad, M. Bütikofer, J. Karderli, B.G. Karlsson, U. Brath, M. Hedenström, G. Gröbner, U.H. Sauer, A. Perrakis, J. Langer, L. Banci, F. Cantini, M. Fragai, D. Grifagni, T. Barthel, Jan Wollenhaupt, M.S. Weiss, A. Robertson, Adriaan Bax, S. Sreeramulu, H. Schwalbe
Nucl. Acids Res.
, 2024
RNA G-quadruplex folding is a multi-pathway process driven by conformational entropy
Marijana U, Burkhart I, Müller S , Schwalbe H, Schwierz N
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© Copyright 2024
Prof. Dr. Harald Schwalbe
Institut für Organische Chemie und Chemische Biologie
Johann Wolfgang Goethe Universität
Max-von-Laue-Str. 7
D-60438 Frankfurt am Main
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